Richard F Keep Selected Research

Thrombin

4/2022	Mechanisms of neuroinflammation in hydrocephalus after intraventricular hemorrhage: a review.
8/2021	Impact of sex differences on thrombin-induced hydrocephalus and white matter injury: the role of neutrophils.
1/2021	The Role of Thrombin in Brain Injury After Hemorrhagic and Ischemic Stroke.
10/2019	Activation of epiplexus macrophages in hydrocephalus caused by subarachnoid hemorrhage and thrombin.
2/2018	Thrombin-induced tolerance against oxygen-glucose deprivation in astrocytes: role of protease-activated receptor-1.
4/2016	Role of Lipocalin-2 in Thrombin-Induced Brain Injury.
1/2016	Effects of Aerobic Capacity on Thrombin-Induced Hydrocephalus and White Matter Injury.
1/2016	Acetazolamide Attenuates Thrombin-Induced Hydrocephalus.
8/2014	Thrombin-induced cerebral hemorrhage: role of protease-activated receptor-1.
6/2014	Role of red blood cell lysis and iron in hydrocephalus after intraventricular hemorrhage.

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Richard F Keep Research Topics

Disease

85	Cerebral Hemorrhage 10/2022 - 01/2002
73	Brain Injuries (Brain Injury) 10/2022 - 01/2002
52	Brain Edema (Cerebral Edema) 01/2021 - 02/2002
31	Hematoma 03/2022 - 01/2002
23	Hydrocephalus (Hydrocephaly) 05/2022 - 03/2006
22	Brain Ischemia (Cerebral Ischemia) 01/2019 - 03/2002
18	Stroke (Strokes) 01/2021 - 02/2004
17	Hemorrhage 05/2022 - 05/2007
13	Edema (Dropsy) 10/2022 - 02/2002
13	Atrophy 02/2022 - 02/2006
13	Infarction (Infarctions) 01/2020 - 04/2002
12	Inflammation (Inflammations) 05/2022 - 11/2003
12	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2021 - 11/2010
12	Ischemia 11/2019 - 06/2006
10	Neuroinflammatory Diseases 04/2022 - 09/2015
9	Iron Overload 01/2020 - 12/2003
7	Reperfusion Injury 09/2016 - 06/2006
6	Ischemic Stroke 01/2021 - 01/2011
6	Hypoxia (Hypoxemia) 04/2016 - 06/2002
6	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 07/2014 - 04/2005
5	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2016 - 01/2003
5	Glioma (Gliomas) 01/2016 - 04/2006
4	Hemorrhagic Stroke 01/2022 - 10/2016
4	Nervous System Diseases (Neurological Disorders) 01/2021 - 01/2002
4	Neoplasms (Cancer) 12/2016 - 01/2008
3	Thrombosis (Thrombus) 01/2022 - 12/2002
3	Intracranial Hemorrhages (Intracranial Hemorrhage) 03/2016 - 08/2014
3	Neurologic Manifestations (Neurological Manifestations) 09/2015 - 02/2004
3	Alzheimer Disease (Alzheimer's Disease) 09/2014 - 11/2012
3	Hyperglycemia 09/2009 - 04/2007
3	Parkinson Disease (Parkinson's Disease) 11/2007 - 01/2005
3	Body Weight (Weight, Body) 07/2007 - 02/2004
2	Hemolysis 01/2020 - 01/2017
2	Encephalitis (Encephalitis, Rasmussen) 01/2020 - 04/2012
2	Central Nervous System Infections (Central Nervous System Infection) 01/2019 - 10/2014
2	Central Nervous System Cavernous Hemangioma 01/2018 - 11/2015
2	Chordoma 01/2018 - 12/2016
2	Infections 04/2015 - 12/2005
2	Neuroblastoma 09/2014 - 05/2008

Drug/Important Bio-Agent (IBA)

53	IronIBA 10/2022 - 02/2002
40	Thrombin FDA Link 04/2022 - 01/2002
26	Hemoglobins (Hemoglobin)IBA 10/2022 - 02/2002
24	Deferoxamine (Desferal)FDA LinkGeneric 03/2022 - 02/2002
17	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2002
10	Lipocalin-2IBA 01/2022 - 04/2013
9	Minocycline (Cyclops)FDA LinkGeneric 05/2022 - 03/2009
7	Ferritins (Ferritin)IBA 01/2021 - 12/2003
6	Clodronic Acid (Clodronate)IBA 05/2022 - 02/2016
6	Liposomes (Liposome)IBA 05/2022 - 02/2016
6	CytokinesIBA 04/2022 - 03/2009
6	Heme Oxygenase-1IBA 10/2021 - 12/2003
6	Neuroprotective AgentsIBA 01/2021 - 01/2011
6	PeroxiredoxinsIBA 01/2021 - 01/2020
6	Glucose (Dextrose)FDA LinkGeneric 02/2018 - 06/2006
6	Oxygen (Dioxygen)IBA 02/2018 - 06/2006
6	Peptide Hydrolases (Proteases)FDA Link 12/2016 - 10/2006
6	salicylhydroxamic acid (SHAM)IBA 01/2016 - 04/2005
6	Tissue Plasminogen Activator (Alteplase)FDA Link 09/2009 - 01/2002
5	Complement System Proteins (Complement)IBA 04/2022 - 07/2005
5	Chelating AgentsIBA 01/2019 - 02/2002
5	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 04/2011 - 11/2003
4	Estrogens (Estrogen)FDA Link 01/2022 - 07/2005
4	Messenger RNA (mRNA)IBA 01/2020 - 01/2002
4	EnzymesIBA 01/2019 - 01/2016
4	Thrombin Receptors (Thrombin Receptor)IBA 01/2016 - 04/2002
4	Cefadroxil (Duricef)FDA LinkGeneric 12/2013 - 12/2005
3	Peptides (Polypeptides)IBA 01/2022 - 07/2014
3	AlbuminsIBA 01/2021 - 04/2007
3	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 01/2021 - 01/2016
3	Pharmaceutical PreparationsIBA 01/2019 - 01/2014
3	SugarsIBA 09/2016 - 01/2011
3	alloseIBA 09/2016 - 01/2011
3	Glutamic Acid (Glutamate)FDA Link 01/2016 - 11/2012
3	Heme (Haem)IBA 01/2016 - 12/2006
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 03/2002
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2014 - 03/2006
3	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2013 - 11/2004
3	Mitogen-Activated Protein KinasesIBA 01/2013 - 09/2009
3	Collagenases (Collagenase)FDA Link 06/2011 - 12/2002
3	Oxidopamine (6 Hydroxydopamine)IBA 11/2007 - 01/2005
3	Transferrin (beta 2 Transferrin)IBA 02/2005 - 12/2003
2	Amyloid (Amyloid Fibrils)IBA 01/2022 - 03/2012
2	Eosine Yellowish-(YS) (Eosin)IBA 01/2022 - 01/2011
2	Hematoxylin (Haematoxylon)IBA 01/2022 - 01/2011
2	Complement C3 (C3 Complement)IBA 01/2021 - 12/2006
2	ChemokinesIBA 01/2020 - 04/2007
2	Hemin (Panhematin)FDA Link 01/2019 - 01/2011
2	Penicillin G (Benzylpenicillin)FDA LinkGeneric 01/2019 - 01/2016
2	ImmunosorbentsIBA 01/2016 - 01/2016
2	Fulvestrant (Faslodex)FDA Link 01/2016 - 07/2005
2	Estrogen ReceptorsIBA 01/2016 - 07/2005
2	Tamoxifen FDA LinkGeneric 01/2016 - 01/2011
2	Antiviral Agents (Antivirals)IBA 04/2015 - 04/2012
2	Anti-Bacterial Agents (Antibiotics)IBA 12/2013 - 01/2008
2	EdaravoneIBA 01/2012 - 02/2008
2	Free Radical ScavengersIBA 01/2012 - 02/2008

Therapy/Procedure

19	Therapeutics 01/2020 - 12/2002
7	Intraventricular Injections 01/2021 - 03/2014
3	Catheters 01/2018 - 07/2002
2	Injections 08/2021 - 01/2021